Description:
Some sex developmental and other disorders may be caused by chromosomal abnormalities . Such derangements can be recognized by obtaining a karyotype from an animal. This entails analyzing the chromosomes for abnormalities. Inconsistencies in the number or arrangement of X- and Y-chromosomes, with respect to the animal’s external genitalia, indicates a sex developmental disorder. (Not all sex developmental disorders are genetic). Other (autosomal) chromosomal abnormalities may be responsible for other developmental defect.

The Section of Medical Genetics offers karyotyping on a case-by-case basis. Either anticoagulated (heparinized) blood, or cultures of a certain cell type, (fibroblasts) are needed. Please contact Dr. Casal (215-898-8894) or Ulana Prociuk (215-573-7545) to discuss the details of a case and to arrange for appropriate sample submission and karyotyping.

Only on prearranged date with a consultation with Dr. Casal or Ulana Prociuk.

Required Samples:
Heparinized blood Fibroblast culture